Baier A., Alikowska E., Szyszka R. 2015. Yeast Asf1 protein as modulator of protein kinase CK2 activity. In: Ahmed K, Issinger O-G, Szyszka R. (Eds.). Protein Kinase CK2 Cellular Function in Normal and Disease States. Advances in Biochemistry in Health and Disease 12. Springer International Publishing. DOI 10.1007/978-3-319-14544-0. Abstract / PDF


Demkowicz S, Kozak W, Daśko M, Masłyk M, Kubiński K, Rachon J. 2015. Phosphate and Thiophosphate Biphenyl Analogs as Steroid Sulfatase Inhibitors. Drug Development Research, DOI: 10.1002/ddr.21245. Abstract / PDF


Kozak W, Daśko M., Wołos A, Masłyk M, Kubiński K, Składanowski A., Misiak M., Rachon J., Demkowicz S. 2015. Synthesis and steroid sulfatase inhibitory activities of N-alkanoyl tyramine phosphates and thiophosphates. RSC Advances 5 (41): 32594-32603. DOI: 10.1039/C5RA01614B. Abstract / PDF


Zapico JM, Puckowska A, Filipiak K, Coderch C, de Pascual-Teresa B, Ramos A. 2015. Org Biomol Chem. Design and synthesis of potent hydroxamate inhibitors with increased selectivity within the gelatinase family. 13(1):142-56. DOI: 10.1039/C4OB01516A. Abstract / PDF




Fabre B., Filipiak K., Coderch C., Zapico J.M., Carbajo R.J., Schott A.K., Pineda-Lucena A., de Pascual-Teresa B., Ramos A. 2014. New clicked thiirane derivatives as gelatinase inhibitors: the relevance of the P1’ segment. RSC Advances 4: 17726-17735. DOI: 10.1039/C3RA46402D. Abstract / PDF


Fabre B, Filipiak K, Díaz N, Zapico JM, Suárez D, Ramos A, de Pascual-Teresa B. 2014. An integrated computational and experimental approach to gaining selectivity for MMP-2 within the gelatinase subfamily. Chembioche 15(3):399-412. Abstract / PDF


Filipiak K, Kubiński K, Hellman U, Ramos A, de Pascual-Teresa B. 2014. Human protein kinase CK2 phosphorylates matrix metalloproteinase 2 and inhibits its activity. Chembiochem 15(13):1873-6. Abstract / PDF


Filipiak K, Hidalgo M, Silvan JM, Fabre B, Carbajo RJ, Pineda-Lucena A, Ramos A, de Pascual-Teresa B, de Pascual-Teresa S. 2014. Dietary gallic acid and anthocyanin cytotoxicity on human fibrosarcoma HT1080 cells. A study on the mode of action. Food Funct. 5(2):381-9. Abstract / PDF


Fuentes I., Stegemann S., Golczyk H., Karcher D., Bock R. 2014. Horizontal genome transfer as an asexual path to the formation of new species. Nature 511: 232-235. DOI: 10.1038/nature13291. Abstract / PDF


Golczyk H., Massouh A., Greiner S. 2014. Translocations of chromosome end-segments and facultative heterochromatin promote meiotic ring formation in evening primroses. Plant Cell 26: 1280-1293. DOI: 10.1105/tpc.114.122655. PDF


Golczyk H., Greiner S., Wanner G., Weihe A., Bock R, Börner T., Herrmann R.G. 2014. Chloroplast DNA in mature and senescing leaves - a reappraisal. Plant Cell 26: 847-854. DOI: 10.1105/tpc.113.117465. PDF


Kozak W, Daśko M., Masłyk M., Pieczykolan J.S., Gielniewski B., Rachon J., Demkowicz S. 2014. Phosphate tricyclic coumarin analogs as steroid sulfatase inhibitors: synthesis and biological activity. RCS Adv 4 (84): 44350-44358. Abstract / PDF


Pieczykolan JS, Kubiński K, Masłyk M, Pawlak SD, Pieczykolan A, Rózga PK, Szymanik M, Gałązka M, Teska-Kamińska M, Zerek B, Bukato K,Poleszak K, Jaworski A, Strożek W, Swider R, Zieliński R. 2014. AD-O53.2-a novel recombinant fusion protein combining the activities of TRAIL/Apo2L and Smac/Diablo, overcomes resistance of human cancer cells to TRAIL/Apo2L, Invest New Drugs 32 (6), 1155-1166. Abstract / PDF


Ward DN, Talley DC, Tavag M, Menji S, Schaughency P, Baier A, Smith PJ. UK-1 and structural analogs are potent inhibitors of hepatitis C virus replication. 2014. Bioorg Med Chem Lett. 15;24(2):609-12. Abstract / PDF


Zhang N, Zhang P, Baier A, Cova L, Hosmane RS. 2014. Dual inhibition of HCV and HIV by ring-expanded nucleosides containing the 5:7-fused imidazo[4,5-e][1,3]diazepine ring system. In vitro results and implications. Bioorg Med Chem Lett. 24(4):1154-7. Abstract / PDF




Fabre B, Filipiak K, Zapico JM, Díaz N, Carbajo RJ, Schott AK, Martínez-Alcázar MP, Suárez D, Pineda-Lucena A, Ramos A, de Pascual-Teresa B. 2013. Progress towards water-soluble triazole-based selective MMP-2 inhibitors. Org Biomol Chem. 14;11(38):6623-41. Abstract / PDF


Godzien J., Garcia-Martinez D., Martinez-Alcazar P., Ruperez Francisco J.; Barbas C. 2013. Effect of a nutraceutical treatment on diabetic rats with targeted and CE-MS non-targeted approaches. Metabolomics 9: S188-S202. DOI: 10.1007/s11306-011-0351-y. Abstract / PDF


Godzien J., Ciborowski M., Whiley L., Legido-Quigley C., Ruperez F.J., Barbas C. 2013. In vial dual extraction liquid chromatography coupled to mass spectrometry applied to streptozotocin-treated diabetic rats. Tips and pitfalls of the method. 2013. J. Chromatography A. 1304:52-60. DOI: 10.1016/j.chroma.2013.07.029. Abstract / PDF


Godzien J., Ciborowski M., Angulo S., Barbas C. 2013. From numbers to a biological sense: How the strategy chosen for metabolomics data treatment may affect final results. A practical example based on urine fingerprints obtained by LC-MS. Electrophoresis 34(19): 2812-2826. DOI: 10.1002/elps.201300053. Abstract / PDF


Golczyk H. 2013. Cytogenetics of Tradescantia spathacea (syn. Rhoeo spathacea): A review. Annales Universitatis Marie Curie-Skłodowska. Sectio C 68 (1): 39-53. DOI: 10.2478/v10067-012-0023-y. PDF


Hartjen P, Höchst B, Heim D, von der Kammer H, Lucke J, Reinholz M, Baier A, Smeets R, Wege H, Borowski P, Schulze Zur Wiesch J. 2013. The NTPase/helicase domain of hepatitis C virus nonstructural protein 3 inhibits protein kinase C independently of its NTPase activity. Cell Mol Biol Lett. 18(3):447-58. DOI: 10.2478/s11658-013-0099-7. Abstract / PDF


Jach M., Łoś R., Maj M., Malm A. (2013) Probiotics – technological and manufacturing aspects. Post. Mikrobiol. 52, 2,161-170.


Jach M., Sajnaga E., Kozak E., Malm A. 2013. Use of yeasts for prevention and therapy. Curr. Issues Pharm. Med. Sci. , 26 (2), 198-202.


Sajnaga E., Jach M., Szyszka R. 2013. Biopierwiastki Sn, Mn, I, Cr, Zn, Cu, Fe – funkcje biologiczne, zapotrzebowanie i suplementacja. Drożdże wzbogacone minerałami. W: Na pograniczu chemii i biologii, H. Koroniak i J. Barciszewski (wyd). Wyd. Naukowe UAM, Poznań


Demkowicz S., Filipiak K., Maslyk M., Ciepielski J., de Pascual Teresa S, Martín-Santamaría S, de Pascual-Teresa B, Ramos A. 2013. New Clicked Full Agonists of the Estrogen Receptor, RSC Adv.: 3, 3697-3706. Abstract / PDF


Sajnaga E., Szyszka R., Kubiński K. 2013. Site-directed mutagenesis in the research of protein kinases – the case of protein CK2. W: Genetic manipulation of DNA and protein, D. Figurski (Ed.). In Tech, 133-166.





Janeczko M., Orzeszko A., Kazimierczuk Z., Szyszka R., Baier A. 2012. K2α and CK2α' subunits differ in their sensitivity to 4,5,6,7-tetrabromo- and 4,5,6,7-tetraiodo-1H-benzimidazole derivatives. Eur J Med Chem. 47(1): 345-50. Abstract / PDF


Jach M. 2012 Frakcjonowanie osocza. Aptekarz Polski 72(50e)


Rodríguez JJ, Filipiak K, Maslyk M, Ciepielski J, Demkowicz S, de Pascual-Teresa S, Martín-Santamaría S, de Pascual-Teresa B, Ramos A. 2012. Towards β-selectivity in functional estrogen receptor antagonists. Org Biomol Chem 10( 36):7334-46. Abstract / PDF


Kouyanou-Koutsoukou S, Baier A, Kolaitis RM, Szyszka R. 2012. Protein kinase CK2 from two higher eukaryotes of economical importance, the mussel Mytilus galloprovincialis and the medfly Ceratitis capitata. Central European Journal of Biology (Impact Factor: 0.63). 01/2012; DOI: 10.2478/s11535-012-0019-2. Abstract / PDF





Golczyk H. 2011. Structural heterozygosity, duplication of telomeric (TTTAGGG)n clusters and B chromosome architecture in Tradescantia virginiana L. Cytogenetic and Genome Research 134: 234-242. DOI: 10.1159/000328915. Abstract / PDF


Golczyk H. 2011. Breakdown of the balanced lethals in Rhoeo. The structure of the alethal Renner complex of the homozygotic stock of Rhoeo. Cytogenetic and Genome Research 134: 229-233. DOI: 10.1159/000328832. Abstract / PDF


Janeczko M., Masłyk M., Szyszka R., Baier A. 2011. Interactions between subunits of protein kinase CK2 and their protein substrates influences its sensitivity to specific inhibitors. Mol Cell Biochem 356(1-2):121-126. Abstract / PDF


Rauwolf U., Greiner S., Mracek., Rauwolf M., Golczyk H., Mohler V., Herrmann R.G., Meurer J. 2011. Uncouping of sexual reproduction from homologous recombination in homozygous Oenothera species. Heredity 107: 87-94. DOI: 10.1038/hdy.2010.171. Abstract / PDF


Golczyk H. 2011. The arrangement of pericentromeres during meiotic prophase I in the permanent translocation heterozygote Rhoeo spathacea. Caryologia 64: 197-202. PDF


Golczyk H. 2011. Cytogenetics of the permanent translocation heterozygote Rhoeo spathacea var. variegata. Implications for complex chromosome rearrangements in Rhoeo. Caryologia 64 (3): 325-334. PDF


Maslyk, M., Zapico, J.M., Swider, R., Martin-Santamaría, S., Ramos, A., de Pascual-Teresa, B. 2011. In the search of a new prototype in CK2 inhibitors design. ARKIVOC, (iii) 54-71. PDF


Swider, R., Maslyk, M., Martin Santamaria, S.,Ramos, A., de Pascual-Teresa, B. 2011. Multisite directed inhibitors of protein kinase CK2. New challenges. Mol Cell Biochem. 356(1-2): 117-9. Abstract / PDF


Kouyanou-Koutsoukou S, Baier A, Kolaitis RM, Maniatopoulou E, Thanopoulou K, Szyszka R. 2011. Cloning and purification of protein kinase CK2 recombinant alpha and beta subunits from the Mediterranean fly Ceratitis capitata. Mol Cell Biochem. 356(1-2):261-7. Abstract / PDF


Kolaiti RM, Baier A, Szyszka R, Kouyanou-Koutsoukou S. 2011 Isolation of a CK2α subunit and the holoenzyme from the mussel Mytilus galloprovincialis and construction of the CK2α and CK2β cDNAs. Mar Biotechnol (NY). (3):505-16. Abstract / PDF


Baier A. 2011. Flaviviral Infections and Potential Targets for Antiviral Therapy Flavivirus Encephalitis. ISBN: 978-953-307-669-0. PDF


Zapico, J. M.; Serra, P.; Garcia-Sanmartin, J.; Filipiak, K.; Carbajo, R. J.; Schott, A. K.; Pineda-Lucena, A.; Martinez, A.; Martin-Santamaria, S.; de Pascual-Teresa, B., Ramos, A.2011. Potent "clicked" MMP2 inhibitors: synthesis, molecular modeling and biological exploration. Organic & Biomolecular Chemistry 9: 4587-4599. DOI: 10.1039/c0ob00852d Abstract / PDF


Zapico J. M., Serra P., Garcia-Sanmartin J., Filipiak K., Martinez, A., Martin-Santamaria, S.; De Pascual-Teresa B., Ramos A.. 2011. Sintesis de inhibidores selectivos de MMP-2 utilizando qumica click. Anales de la Real Academia de Nacional de Farmacia 77: 99-117. PDF






Frączyk, T., Kubinski, K., Maslyk, M., Ciesla, J., Hellman, U., Shugar, D., Rode, W. 2010. Phosphorylation of Thymidylate Synthase from Various Sources by Human Protein Kinase CK2 and its Catalytic Subunits, Bioorg. Chem., 38(3): 124-31. Abstract / PDF


Jach M. 2010 Praktyczne aspekty współpracy nauki i przemysłu. W: „Przedsiębiorczość akademicka czynnikiem rozwoju regionu i kraju”, Wyd. LBS Lublin, maj 2010.


Malm A., Łoś R., Jach M., Szymańska J., Gziut N. 2010 Probiotics in the 21st century. Zdr.Pub. 120(2):194-198.


Martín-Santamaría, S., Rodríguez, J.J., Maslyk, M., de Pascual-Teresa, B., Ramos, A. 2010. SERMs: un largo camino desde el tamoxifeno hasta las nuevas estrategias para el diseño de fármacos más selectivos. Anales de Quimica 106(3): 169-252. PDF





Maslyk M., Kochanowicz E., Zielinski R., Kubinski K., Hellman U., Szyszka R. 2008. Yeast surviving factor Svf1 as a new interacting partner, regulator and in vitro substrate of protein kinase CK2. Mol Cell Biochem 312(1-2): 61-9. Abstract / PDF





Domanska K., Zielinski R., Kubinski K., Sajnaga E., Maslyk M, Bretner M., Szyszka R. 2005. Different properties of four molecular forms of protein kinase CK2 from Saccharomyces cerevisiae. Acta Biochimica Polonica 52, 947-951. PDF